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Silvia Caballero: A Rising Star In The Microbiome Field

It has been more than a decade since scientists have discovered antibiotic drug resistance species. It is believed that in the upcoming 20 years, nearly everyone is going to get affected by these resistant variants of microbes or superbugs. That is why Silvia Caballero feels an urgent rush to develop methods to contain such bugs. No matter how fit you are if you’re abruptly consuming antibiotics, you are certainly creating a home for such superbugs.

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Dr. Silvia Caballero pursued her Bachelor’s of Arts- Biological Science (Major) from Hunter College, NYC. Later, she completed her doctoral study (Ph.D.) in Microbiology and Immunology, from Weill Medical College of Cornell University, NYC. Having a great academic background, she kept herself busy in other extracurricular activities too. With such a great research background she worked in the various top-notch institutes such as Harvard, Cold Spring Harbor Laboratory, and many more. She was among the one to find out the species of microbes residing inside the human gut that could fight back against the antibiotic-resistant bacteria.



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While working in a lab at Memorial Sloan-Kettering Cancer Center, New York. Caballero developed a mice whose entire gut system was the replica of the human system infected by superbugs. With the help of bioinformatics tools, she could find out the microbes that help in the evasion of such superbugs while replicating inside the gut system, ultimately she developed the mice’s body and its immune system as armor against such invaders or superbugs.

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Now working as Associate Director, Infectious Disease at Vedanta Biosciences in Cambridge, Massachusetts, Caballero is working to identify the bacterial species that could contain the major three strains of superbugs that are often found in the hospitals and nursing homes. She also heads the company’s multidrug-resistant organism decolonization program, with a vision to do for people what Caballero did for the mice, her treatment protocol might find a way into early trials within the upcoming years.